The study of gene regulation, disease and the genetics of organisms and populations is revolutionising the research fields of development, reproduction, biotechnology and medicine.
Population and Quantitative Genetics
The Population and Quantitative Genetics Group investigate the causes and consequences of genetic variation in natural populations. A broad range of statistical techniques such as Genome-Wide Association and Genomic Selection methods are used to explore the pattern and effect of molecular variation at the whole genome level. Biological models of interest include humans, plants and insects with an emphasis on biological questions related to human health and agriculture.
Reproduction and Development
The Reproduction and Development Groups study the very beginnings of life and factors that influence the growth and health of the embryo, foetus and offspring.
Basic and biomedical research of mammalian systems focuses on the genetics and molecular control of early embryo development, sexual differentiation, environmental disruptors of development, stem cell biology, comparative genomics and reproductive physiology.
Reproduction is the science of the transmission of life!
The Cardiovascular Physiology Group studies how blood vessels are damaged in cardiovascular disease and investigates new treatments for vascular dysfunction. Diseases of interest include; acute heart failure, hypertension in pregnancy and diabetes.
Developmental and Cellular Genetics
The living cell possesses extraordinary capabilities that allow it to sense and respond to its environment, metabolise nutrients required for growth and division and undergo changes in cell shape and function. All of these processes are under the control of the hereditary instructions or genes it expresses, from among the thousands in its genome.
Microbes are both vital and problematic. Without them our world couldn’t exist, but some cause us monumental grief. Understanding microbes helps us manage our environment, stay healthy and look after our crops, livestock and food supplies. Genetic tools have given us powerful means to understand these invisible organisms that impact our lives in myriad ways.
Plant Functional GenomicsThe Roessner research group is interested in understanding how Australian crops, such as cereals and legumes, adapt and tolerate challenging environmental conditions including water and nutrient deficiencies, salinity, heat or cold. We are applying systems biology approaches such as genomics, transcriptomics, lipidomics and metabolomics to compare the biochemical responses of crop plants with contrasting tolerance levels to identify novel adaptation and tolerance mechanisms.