BioSciences Visions Seminar - Professor Ute Roessner - Imaging mass spectrometry – where are metabolites located?
Imaging Mass Spectrometry (IMS) is a novel technique allowing the measurement of the spatiotemporal distribution of many biomolecules, including lipids, in thin sections of biological tissues. The growing field of spatial lipidomics and metabolomics is developing and adopting IMS as a complementary analytical tool to conventional ‘omics analyses of crude tissue extracts. Here we present the advantages and disadvantages of IMS and describe potential applications of spatial metabolite and lipid analysis in different biological tissues such as from mammals or plants. We will discuss how IMS will contribute to our increasing knowledge base of biological systems by providing information on the spatial distribution.
Host: Professor Raoul Mulder
Followed by sandwiches BioSciences 2 Tea Room. Please let the host know if you would like the opportunity to meet the speaker before or after the seminar.
Professor Ute Roessner, School of BioSciences
Professor Ute Roessner
School of BioSciences
Prof Roessner obtained her a PhD in Plant Biochemistry at the Max Planck Institute for Molecular Plant Physiology in Germany in 2001, where she developed novel GCMS methods to analyse metabolites in plants. Together with the application of sophisticated data mining the field of metabolomics was born and is today an important tool in biological sciences, systems biology and biomarker discovery. In 2003 she moved to Australia where she established a GCMS and LCMS based metabolomics platform as part of the Australian Centre for Plant Functional Genomics for which she led the node at the University of Melbourne. In addition, since 2007 Prof Roessner has been involved in the setup of Metabolomics Australia (MA), a federal and state government funded national metabolomics service facility and now leads the MA node at The University of Melbourne. In 2013 Prof Roessner was awarded an Australian Research Council Future Fellowship to apply Imaging Mass Spectrometry for spatial metabolite and lipid analyses to solve biological questions. Currently she is the Head of School, School of BioSciences, University of Melbourne.