Dr Michael Murray

Research interests

Developmental genetics of Drosophila

My lab studies the genetic regulation of morphogenesis with a focus on epithelial plasticity: the ability of cells to change from stationary epithelial cells to migratory cells and back again. These mechanisms play crucial roles during development, cancer and wound-healing.

  • Genetic regulation of epithelial-mesenchymal plasticity (EMT/MET) during Drosophila development
  • molecular mechanisms of epithelial polarisation in Drosophila and mammalian cells
  • Netrins and wound healing
  • Modelling cancer metastasis in the fly
  • Hox gene regulation of epithelial morphogenesis.

Research projects

  • How is netrin upregulated in response to wounding?
  • The role of wound-healing pathways in epithelial homeostasis

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