Insecticide biology, neurogenetics, parasitic biology of the blowfly
The focus of our research is to understand, safeguard and improve insect control strategies. Using both model and pest insects, we apply a mixture of genetics, 'omics' and molecular techniques such as CRISPR to interrogate:
- Insecticide biology: determining how insecticides work, what the responses of insects are to acute and chronic exposures and how insects might become resistant
- Neurogenetics: examining nicotinic acetylcholine receptor assembly and trafficking, how specific mutations impact receptor function and the role of these receptors in insect behaviour and development
- Parasitic biology of the Australian sheep blowfly, Lucilia cuprina: understanding how flies detect their hosts, establish myiasis (flystrike) and evade host responses.
- Genetic analysis of neuronal circuits impacted by insecticides
- Structural and functional studies on the nAChR subunits using domain swapping and CRISPR
- Parasitic biology of the Australian sheep blowfly, Lucilia cuprina;