Malaria and endosymbiosis
The McFadden Lab identifies new drug targets in the malaria parasite and seeks strategies to control the ever increasing problem of drug resistance. We work with human and rodent malaria models and have a complete life cycle facility in which we infect mosquitoes to study transmission of the disease from vertebrate to vertebrate via insects.
- From symbiont to parasite - sugar transporters and the origins of malaria parasites
- The genetic trap - how malaria's complex life cycle can be used to develop resistance-proof drugs
- When mosquitoes get malaria - understanding host parasite interactions during transmission
- Molecular control of organellar inheritance in apicomplexan parasites